|Tested species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RSKPGKPRSTTN) corresponding to the internal amino acids of GALR1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-0.3 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with bovine, canine, human and mouse based on sequence homology.
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Antinociceptive roles of galanin receptor 1 in nucleus accumbens of rats in a model of neuropathic pain.
PA5-18629 was used in western blot to elucidate how galanin suppresses pain in rats.
|Duan H,Zhang Y,Zhang XM,Xu HH,Shu J,Xu SL||Journal of neuroscience research (93:1542)||2015|