Proteintech

GAP43 Polyclonal Antibody

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GAP43 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 16971-1-AP ( GAP43 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

GAP43 Antibody in Western Blot (WB) — A549 cells and mouse retina tissue were subjected to SDS PAGE followed by western blot with 16971-1-AP (GAP43 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

GAP43 Antibody in Immunoprecipitation (IP) — IP result of anti-GAP43 (IP:16971-1-AP, 4ug; Detection:16971-1-AP 1:500) with mouse brain tissue lysate 6000ug.

Product Details

16971-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:600-1:3000	View 6 publications 6 publications
Immunohistochemistry (IHC)	-	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunocytochemistry (ICC/IF)	-	View 1 publication 1 publication
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	GAP43 Fusion Protein Ag9294 (1-238 aa encoded by BC007936) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.4 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MLCCMRRTK QVEKNDDDQK IEQDGIKPED KAHKAATKIQ ASFRGHITRK KLKGEKKDDV QAAEAEANKK DEAPVADGVE KKGEGTTTAE AAPATGSKPD EPGKAGETPS EEKKGEGDAA TEQAAPQAPA SSEEKAGSAE TESATKASTD NSPSSKAEDA PAKEEPKQAD VPAAVTAAAA TTPAAEDAAA KATAQPPTET GESSQAEENI EAVDETKPKE SARQDEGKEE EPEADQEHA (1-238 aa encoded by BC007936 )

Target Information

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise.

Frontiers in cellular neuroscience

Wu Z,Li X,Zhang Y,Tong D,Wang L,Zhao P

Thu Oct 01 00:00:00 EDT 2020

Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.

Acta histochemica

Wang Y,Liu Y,Li Y,Liu B,Wu P,Xu S,Shi H

Tue Jan 01 00:00:00 EST 2019

Neurochemical research

Ding D,Zhang P,Liu Y,Wang Y,Sun W,Yu Z,Cheng Z,Wang Y

Sat Dec 01 00:00:00 EST 2018

Neurochemical research

Ding D,Zhang P,Liu Y,Wang Y,Sun W,Yu Z,Cheng Z,Wang Y

Sat Dec 01 00:00:00 EST 2018

An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu J,Wang L,Du Y,Liu S

Sun Oct 01 00:00:00 EDT 2017

β-Caryophyllene protects in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.

Journal of neurochemistry

Tian X,Peng J,Zhong J,Yang M,Pang J,Lou J,Li M,An R,Zhang Q,Xu L,Dong Z

Thu Dec 01 00:00:00 EST 2016

Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.

Neuroscience

Yu J,Lin S,Wang M,Liang L,Zou Z,Zhou X,Wang M,Chen P,Wang Y

Sat Oct 01 00:00:00 EDT 2016

Bone marrow mesenchymal stem cells repair spinal cord ischemia/reperfusion injury by promoting axonal growth and anti-autophagy.

Neural regeneration research

Yin F,Meng C,Lu R,Li L,Zhang Y,Chen H,Qin Y,Guo L

Mon Sep 15 00:00:00 EDT 2014

Bioinformatics

Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1

Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46

UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837

Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432

Function(s)