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Product Details
PA5-22896
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Chicken,
Fruit fly,
Horse,
Human,
Mouse,
Non-human primate,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 216-226 of rat/mouse GAP-43, (C)-KEDPEADQEHA coupled to maleimide-activated KLH.
Conjugate
Excitation/Emission Max
651/673 nm
View spectra
Form
Liquid
Concentration
0.70 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
50mM sodium borate
Contains
0.05% sodium azide
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152058
Product Specific Information
This antibody does not react with xenopus samples.
Suggested positive control: embryonic nervous tissue, brain, injured nerve.
Target Information
GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1
Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46
UniProt ID: (Chicken) P35001, (Human) P17677, (Bovine) P06836, (Rat) P07936, (Mouse) P06837
Entrez Gene ID: (Chicken) 427955, (Dog) 478572, (Horse) 100061125, (Human) 2596, (Pig) 100623423, (Bovine) 281777, (Rat) 29423, (Mouse) 14432
nervous system development
axon guidance
glial cell differentiation
axon choice point recognition
regulation of growth
tissue regeneration
cell fate commitment
regulation of filopodium assembly
axon development
axon regeneration
multicellular organism development
cell differentiation
protein kinase C-activating G-protein coupled receptor signaling pathway
response to wounding
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