Product References
Time-limited alterations in cortical activity of a knock-in mouse model of KCNQ2-related developmental and epileptic encephalopathy.
The Journal of physiology
Biba-Maazou N,Becq H,Pallesi-Pocachard E,Sarno S,Granjeaud S,Montheil A,Kurz M,Villard L,Milh M,Santini PL,Aniksztejn L
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Sun May 01 00:00:00 EDT 2022
RIP3 Contributes to Cardiac Hypertrophy by Influencing MLKL-Mediated Calcium Influx.
Oxidative medicine and cellular longevity
Xue H,Shi H,Zhang F,Li H,Li C,Han Q
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Tue Apr 26 00:00:00 EDT 2022
C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation.
Human molecular genetics
van Ingen E,van den Homberg DAL,van der Bent ML,Mei H,Papac-Milicevic N,Kremer V,Boon RA,Quax PHA,Wojta J,Nossent AY
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Thu Mar 31 00:00:00 EDT 2022
CRISPR-Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus.
Biotechnology for biofuels
Löbs AK,Engel R,Schwartz C,Flores A,Wheeldon I
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Fri Mar 18 00:00:00 EDT 2022
An Orally Bioavailable and Highly Efficacious Inhibitor of CDK9/FLT3 for the Treatment of Acute Myeloid Leukemia.
Cancers
Anshabo AT,Bantie L,Diab S,Lenjisa J,Kebede A,Long Y,Heinemann G,Karanjia J,Noll B,Basnet SKC,Li M,Milne R,Albrecht H,Wang S
PA1-987 was used in Western Blot to demonstrate the potential of CDDD11-8 towards the future development of a novel AML treatment.
Tue Feb 22 00:00:00 EST 2022
Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity.
Proceedings of the National Academy of Sciences of the United States of America
Wang S,Zhao L,Zhang X,Zhang J,Shang H,Liang G
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Tue Jan 11 00:00:00 EST 2022
Small molecule splicing modifiers with systemic HTT-lowering activity.
Nature communications
Bhattacharyya A,Trotta CR,Narasimhan J,Wiedinger KJ,Li W,Effenberger KA,Woll MG,Jani MB,Risher N,Yeh S,Cheng Y,Sydorenko N,Moon YC,Karp GM,Weetall M,Dakka A,Gabbeta V,Naryshkin NA,Graci JD,Tripodi T,Southwell A,Hayden M,Colacino JM,Peltz SW
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Wed Dec 15 00:00:00 EST 2021
Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer.
Journal of nanobiotechnology
Pan X,Qi Y,Du Z,He J,Yao S,Lu W,Ding K,Zhou M
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Sat Nov 27 00:00:00 EST 2021
Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase.
The Journal of biological chemistry
Peshenko IV,Olshevskaya EV,Dizhoor AM
PA1-987 was used in Western Blot to demonstrate that aberrant activation of the retinal membrane guanylyl cyclase (RetGC) by its calcium-sensor proteins (guanylyl cyclase-activating protein [GCAP]) causes this retinal degeneration and that RD3 protects photoreceptors by preventing such activation.
Fri Oct 01 00:00:00 EDT 2021
Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.
Scientific reports
Qu J,Fourman S,Fitzgerald M,Liu M,Nair S,Oses-Prieto J,Burlingame A,Morris JH,Davidson WS,Tso P,Bhargava A
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Thu Jun 24 00:00:00 EDT 2021
Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.
Scientific reports
Qu J,Fourman S,Fitzgerald M,Liu M,Nair S,Oses-Prieto J,Burlingame A,Morris JH,Davidson WS,Tso P,Bhargava A
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Thu Jun 24 00:00:00 EDT 2021
Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages.
Nature communications
Zhao L,Wang S,Xu M,He Y,Zhang X,Xiong Y,Sun H,Ding H,Geng W,Shang H,Liang G
PA1-987 was used in Western Blot to report the mechanisms behind HIV-1 accessory protein, Vpr, enhancement of macrophage infection.
Thu Jun 17 00:00:00 EDT 2021
Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins.
Frontiers in neurology
Jiang L,Zhao J,Cheng JX,Wolozin B
PA1-987 was used in Western Blotting to explore the actions of two distinct types of tau aggregates, tau oligomers and tau fibrils in primary neuron cultures expressing human 4R0N tau.
Fri Jun 04 00:00:00 EDT 2021
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Cell death & disease
Huangfu J,Hao C,Wei Z,Wormstone IM,Yan H,Fan X
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Fri Apr 09 00:00:00 EDT 2021
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Cell death & disease
Huangfu J,Hao C,Wei Z,Wormstone IM,Yan H,Fan X
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Fri Apr 09 00:00:00 EDT 2021
Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
DNA and cell biology
Cruz A,Ferian A,Alves PKN,Silva WJ,Bento MR,Gasch A,Labeit S,Moriscot AS
PA1-987 was used in Western Blotting to study the impact of leucine supplementation on myostatin expression using male rats.
Mon Nov 02 00:00:00 EST 2020
lncRNA ZEB1-AS1 Mediates Oxidative Low-Density Lipoprotein-Mediated Endothelial Cells Injury by Post-transcriptional Stabilization of NOD2.
Frontiers in pharmacology
Xu X,Ma C,Duan Z,Du Y,Liu C
PA1-987 was used in Western Blotting to analyse a poorly characterised human long non-coding RNA, ZEB1 antisense 1.
Thu Oct 01 00:00:00 EDT 2020
Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.
Frontiers in neuroscience
Lin Z,Gu Y,Zhou R,Wang M,Guo Y,Chen Y,Ma J,Xiao F,Wang X,Tian X
PA1-987 was used in Western Blotting to investigate the use of exosomal proteins as biomarkers for epilepsy.
Mon Sep 28 00:00:00 EDT 2020
miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock.
Scientific reports
Wu F,Wang JY,Chao W,Sims C,Kozar RA
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Fri Sep 25 00:00:00 EDT 2020
miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock.
Scientific reports
Wu F,Wang JY,Chao W,Sims C,Kozar RA
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Fri Sep 25 00:00:00 EDT 2020
Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma.
Cancers
Zhai Z,Samson JM,Yamauchi T,Vaddi PK,Matsumoto Y,Dinarello CA,Ravindran Menon D,Fujita M
PA1-987 was used in Western Blotting to investigate the role of inflammasome sensor NLRP1 in acquired drug resistance to temozolomide (TMZ) in melanoma.
Fri Sep 04 00:00:00 EDT 2020
S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson's disease.
PloS one
Wu W,Sung CC,Yu P,Li J,Chung KKK
PA1-987 was used in Western Blotting to demonstrate that GRK6 and CK2α can be S-nitrosylated by nitric oxide (NO) both in vitro and in vivo.
Mon Jul 20 00:00:00 EDT 2020
Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40.
American journal of physiology. Endocrinology and metabolism
Zhang L,Chen Z,Wang Y,Tweardy DJ,Mitch WE
PA1-987 was used in Western Blot to conclude that Stat3 activation in muscle increases IR in mice.
Fri May 01 00:00:00 EDT 2020
RNA Sequence Analyses throughout the Course of Mouse Cardiac Laminopathy Identify Differentially Expressed Genes for Cell Cycle Control and Mitochondrial Function.
Scientific reports
Shao Z,Koh W,Ni Y,Li W,Agatisa-Boyle B,Merkurjev D,Tang WHW
PA1-987 was used in Western Blotting to demonstrate that impaired oxidative phosphorylation takes place at the early disease stage and worsens with disease progression in familial dilated cardiomyopathy.
Mon Apr 20 00:00:00 EDT 2020
miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1.
Oncology reports
Lin J,Shen J,Yue H,Cao Z
PA1-987 was used in Western Blotting to identify that the downregulation of TPM1 and deactivation of the Bcl-2/P53 signaling pathways by miR-183-5p.1, promotes proliferation, migration and invasion in gastric cancer.
Sun Dec 01 00:00:00 EST 2019
Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent.
Molecules (Basel, Switzerland)
Hackler L,Gyuris M,Huzián O,Alföldi R,Szebeni GJ,Madácsi R,Knapp L,Kanizsai I,Puskás LG
PA1-987 was used in Western Blotting to show that the enantiomers of Q134 showed potent and similar activity in all tested assays.
Sat Nov 23 00:00:00 EST 2019
Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.
mBio
Winstel V,Schneewind O,Missiakas D
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Tue Nov 12 00:00:00 EST 2019
lncRNA ZEB1-AS1 promotes migration and metastasis of bladder cancer cells by post-transcriptional activation of ZEB1.
International journal of molecular medicine
Zhao X,Wang D,Ding Y,Zhou J,Liu G,Ji Z
PA1-987 was used in Western Blotting to determine the role of zinc finger E-box binding homeobox 1-antisense in bladder cancer progression and metastasis.
Mon Jul 01 00:00:00 EDT 2019
Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer.
Oncology letters
Nolasco-Quiroga M,Rosas-Díaz M,Moreno J,Godínez-Aguilar R,López-Ibarra MJ,Piña-Sánchez P,Alvarado-Cabrero I,Vázquez-Gómez G,Rocha-Zavaleta L,Arenas-Aranda D,Salamanca-Gómez F
PA1-987 was used in Western Blotting to analyse the expression level of focal adhesion kinase isoforms in ovarian cancer.
Sat Jun 01 00:00:00 EDT 2019
lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma.
International journal of oncology
Chen F,Qi S,Zhang X,Wu J,Yang X,Wang R
PA1-987 was used in Western Blotting to investigate the regulatory model of the long noncoding RNA placenta-specific protein 2 upregulation in oral squamous cell carcinoma, and its function in OSCC malignant progression.
Mon Apr 01 00:00:00 EDT 2019
Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening.
Scientific reports
Martin DDO,Kanuparthi PS,Holland SM,Sanders SS,Jeong HK,Einarson MB,Jacobson MA,Thomas GM
PA1-987 was used in Western Blotting to report that DLK subcellular localization in non-neuronal cells is highly palmitoylation-dependent and can thus serve as a proxy readout to identify inhibitors of DLK palmitoylation by High Content Screening.
Wed Mar 06 00:00:00 EST 2019
Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer.
Molecular cancer
Dong H,Hu J,Zou K,Ye M,Chen Y,Wu C,Chen X,Han M
PA1-987 was used in Western Blotting to identify the regulatory role of long non-coding RNA in trastuzumab resistance and accompanied Epithelial-mesenchymal Transition process in advanced human epidermal growth factor receptor 2-positive breast cancer.
Tue Jan 08 00:00:00 EST 2019
Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines.
Virulence
Liu J,Ma'ayeh S,Peirasmaki D,Lundström-Stadelmann B,Hellman L,Svärd SG
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Mon Dec 31 00:00:00 EST 2018
Exploration of the regulation and control mechanisms of miR-145 in trophoblast cell proliferation and invasion.
Experimental and therapeutic medicine
Chi Z,Zhang M
PA1-987 was used in Western Blotting to investigate the functions of miR-145 in preeclampsia.
Sat Dec 01 00:00:00 EST 2018
Transgenic overexpression of furin increases epileptic susceptibility.
Cell death & disease
Yang Y,He M,Tian X,Guo Y,Liu F,Li Y,Zhang H,Lu X,Xu D,Zhou R,Ma Y,Wang W,Chen G,Hu Y,Wang X
PA1-987 was used in Western Blotting to study the role of furin expression in epilepsy.
Wed Oct 17 00:00:00 EDT 2018
Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose-phosphate pathways in embryonic heart.
The Journal of biological chemistry
Peoples JNR,Maxmillian T,Le Q,Nadtochiy SM,Brookes PS,Porter GA,Davidson VL,Ebert SN
PA1-987 was used in Western Blotting to study the effects of adrenergic hormones on metabolism in the embryonic heart.
Fri May 04 00:00:00 EDT 2018
Rapid estrogen receptor-α signaling mediated by ERK activation regulates vascular tone in male and ovary-intact female mice.
American journal of physiology. Heart and circulatory physiology
Kim SC,Boese AC,Moore MH,Cleland RM,Chang L,Delafontaine P,Yin KJ,Lee JP,Hamblin MH
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Thu Feb 01 00:00:00 EST 2018
Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.
Cancer cell
Guler GD,Tindell CA,Pitti R,Wilson C,Nichols K,KaiWai Cheung T,Kim HJ,Wongchenko M,Yan Y,Haley B,Cuellar T,Webster J,Alag N,Hegde G,Jackson E,Nance TL,Giresi PG,Chen KB,Liu J,Jhunjhunwala S,Settleman J,Stephan JP,Arnott D,Classon M
PA1-987 was used in Western Blotting to show that the genomes of a cancer cell subpopulation that survives treatment with otherwise lethal drugs, the drug-tolerant persisters, exhibit a repressed chromatin state.
Mon Aug 14 00:00:00 EDT 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
PA1-987 was used in Western Blotting to investigate the effects and underlying mechanism of chlorogenic acid on IL-1Β-induced osteoarthritis chondrocytes.
Tue Aug 01 00:00:00 EDT 2017
Impact of R264C and R264H polymorphisms in human aromatase function.
The Journal of steroid biochemistry and molecular biology
Baravalle R,Di Nardo G,Bandino A,Barone I,Catalano S,Andò S,Gilardi G
PA1987 was used in western blot to characterize cytochrome P450 aromatase mutations
Wed Mar 01 00:00:00 EST 2017
Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer.
Nucleic acids research
Wagner S,Herrmannová A,Šikrová D,Valášek LS
Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot
Thu Dec 15 00:00:00 EST 2016
Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering.
Biomedical materials (Bristol, England)
Jain S,Krishna Meka SR,Chatterjee K
PA1987 was used in western blot to create curcumin-eluting tissue scaffolds and explore their potential in bone tissue regeneration
Thu Oct 06 00:00:00 EDT 2016
Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth.
Biology of reproduction
Nadeau-Vallée M,Boudreault A,Leimert K,Hou X,Obari D,Madaan A,Rouget R,Zhu T,Belarbi L,Brien MÈ,Beaudry-Richard A,Olson DM,Girard S,Chemtob S
PA1987 was used in western blot to measure the expression and function of neuromedin U receptor 2 and its ligands in gestational tissues
Thu Sep 01 00:00:00 EDT 2016
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator.
British journal of pharmacology
Hyrsova L,Smutny T,Carazo A,Moravcik S,Mandikova J,Trejtnar F,Gerbal-Chaloin S,Pavek P
PA1-987 was used in western blot to study down-regulation of organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator by the pregane X receptor
Sun May 01 00:00:00 EDT 2016
DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.
Developmental biology
Ajima R,Bisson JA,Helt JC,Nakaya MA,Habas R,Tessarollo L,He X,Morrisey EE,Yamaguchi TP,Cohen ED
PA1-987 was used in Western Blotting to investigate the Wnt-associated pathways induced by DAAM1 and DAAM2 in the myocardium.
Tue Dec 01 00:00:00 EST 2015
An animal model for chorioamnionitis at term.
American journal of obstetrics and gynecology
Dell'Ovo V,Rosenzweig J,Burd I,Merabova N,Darbinian N,Goetzl L
PA1-987 was used in western blot to develop an animal model for intrapartum inflammation at term.
Tue Sep 01 00:00:00 EDT 2015
Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.
Developmental biology
Bisson JA,Mills B,Paul Helt JC,Zwaka TP,Cohen ED
PA1-987 was used in western blot to study the regulation of the canonical Wnt pathway and its effect on cardiac progenitor development
Sun Feb 01 00:00:00 EST 2015
Intestinal fatty acid binding protein (fabp2) in Atlantic salmon (Salmo salar): Localization and alteration of expression during development of diet induced enteritis.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
Venold FF,Penn MH,Thorsen J,Gu J,Kortner TM,Krogdahl A,Bakke AM
PA1-987 was used in western blot to study the expression of intestinal fatty acid binding proteins FABP2a1, FABP2a2 and FABPb during diet-induced enteritis in Atlantic salmon
Tue Jan 01 00:00:00 EST 2013
Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure.
The Journal of physiology
Briston SJ,Caldwell JL,Horn MA,Clarke JD,Richards MA,Greensmith DJ,Graham HK,Hall MC,Eisner DA,Dibb KM,Trafford AW
PA1-987 was used in western blot to study the mechanism for the dysfunctional excitation-contraction coupling in heart failure
Tue Mar 15 00:00:00 EDT 2011
An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Asundi J,Reed C,Arca J,McCutcheon K,Ferrando R,Clark S,Luis E,Tien J,Firestein R,Polakis P
PA1-987 was used in western blot to evaluate an antibody-drug conjugate for melanoma treatment
Tue Mar 01 00:00:00 EST 2011