Invitrogen

GAPDH Polyclonal Antibody

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GAPDH Antibody in Western Blot (WB) — Western blot analysis was performed on whole cell extracts (30 µg lysate) of A-431 (Lane 1), COS-7 (Lane 2), MDCK (Lane 3), PC-3 (Lane 4) and tissue extract (30 µg lysate) of Ms Brain (Lane 5). The blot was probed with Anti-GAPDH Polyclonal Antibody (Product # PA1-987, 1:1,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 37 kDa band corresponding to GAPDH was observed across the cell lines tested. Known quantity of protein samples were electrophoresed using Novex® NuPAGE® 10% Bis-Tris gel (Product # NP0302BOX), XCell SureLock™ Electrophoresis System (Product # EI0002) and Novex® Sharp Pre-Stained Protein Standard (Product # LC5800). Resolved proteins were then transferred onto a nitrocellulose membrane with iBlot® 2 Dry Blotting System (Product # IB21001). The membrane was probed with the relevant primary and secondary Antibody following blocking with 5% skimmed milk. Chemiluminescent detection was performed using Pierce™ ECL Western Blotting Substrate (Product # 32106).

Product Details

PA1-987

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:5,000	View 47 publications 47 publications

Product Specifications
Species Reactivity	Dog, Human, Mouse, Non-human primate, Rat
Published species	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide: A(126) DAPMFVMGVN HEKY(140)
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS with 1mg/mL BSA
Contains	0.05% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2107311

Product Specific Information

PA1-987 detects rat GAPDH. Shares 100% sequence homology with human and mouse.

PA1-987 has been used successfully in Western blotting. By Western blot this antibody specifically detects a ~36 kDa protein representing GAPDH.

PA1-987 immunizing peptide corresponds to amino acid residues 126-140 from human GAPDH.

Target Information

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Time-limited alterations in cortical activity of a knock-in mouse model of KCNQ2-related developmental and epileptic encephalopathy.

The Journal of physiology

Biba-Maazou N,Becq H,Pallesi-Pocachard E,Sarno S,Granjeaud S,Montheil A,Kurz M,Villard L,Milh M,Santini PL,Aniksztejn L

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Sun May 01 00:00:00 EDT 2022

RIP3 Contributes to Cardiac Hypertrophy by Influencing MLKL-Mediated Calcium Influx.

Oxidative medicine and cellular longevity

Xue H,Shi H,Zhang F,Li H,Li C,Han Q

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Tue Apr 26 00:00:00 EDT 2022

C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation.

Human molecular genetics

van Ingen E,van den Homberg DAL,van der Bent ML,Mei H,Papac-Milicevic N,Kremer V,Boon RA,Quax PHA,Wojta J,Nossent AY

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Thu Mar 31 00:00:00 EDT 2022

CRISPR-Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus.

Biotechnology for biofuels

Löbs AK,Engel R,Schwartz C,Flores A,Wheeldon I

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Fri Mar 18 00:00:00 EDT 2022

An Orally Bioavailable and Highly Efficacious Inhibitor of CDK9/FLT3 for the Treatment of Acute Myeloid Leukemia.

Cancers

Anshabo AT,Bantie L,Diab S,Lenjisa J,Kebede A,Long Y,Heinemann G,Karanjia J,Noll B,Basnet SKC,Li M,Milne R,Albrecht H,Wang S

PA1-987 was used in Western Blot to demonstrate the potential of CDDD11-8 towards the future development of a novel AML treatment.

Tue Feb 22 00:00:00 EST 2022

Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity.

Proceedings of the National Academy of Sciences of the United States of America

Wang S,Zhao L,Zhang X,Zhang J,Shang H,Liang G

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Tue Jan 11 00:00:00 EST 2022

Small molecule splicing modifiers with systemic HTT-lowering activity.

Nature communications

Bhattacharyya A,Trotta CR,Narasimhan J,Wiedinger KJ,Li W,Effenberger KA,Woll MG,Jani MB,Risher N,Yeh S,Cheng Y,Sydorenko N,Moon YC,Karp GM,Weetall M,Dakka A,Gabbeta V,Naryshkin NA,Graci JD,Tripodi T,Southwell A,Hayden M,Colacino JM,Peltz SW

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Wed Dec 15 00:00:00 EST 2021

Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer.

Journal of nanobiotechnology

Pan X,Qi Y,Du Z,He J,Yao S,Lu W,Ding K,Zhou M

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Sat Nov 27 00:00:00 EST 2021

Retinal degeneration-3 protein attenuates photoreceptor degeneration in transgenic mice expressing dominant mutation of human retinal guanylyl cyclase.

The Journal of biological chemistry

Peshenko IV,Olshevskaya EV,Dizhoor AM

PA1-987 was used in Western Blot to demonstrate that aberrant activation of the retinal membrane guanylyl cyclase (RetGC) by its calcium-sensor proteins (guanylyl cyclase-activating protein [GCAP]) causes this retinal degeneration and that RD3 protects photoreceptors by preventing such activation.

Fri Oct 01 00:00:00 EDT 2021

Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.

Scientific reports

Qu J,Fourman S,Fitzgerald M,Liu M,Nair S,Oses-Prieto J,Burlingame A,Morris JH,Davidson WS,Tso P,Bhargava A

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Thu Jun 24 00:00:00 EDT 2021

Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue.

Scientific reports

Qu J,Fourman S,Fitzgerald M,Liu M,Nair S,Oses-Prieto J,Burlingame A,Morris JH,Davidson WS,Tso P,Bhargava A

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Thu Jun 24 00:00:00 EDT 2021

Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages.

Nature communications

Zhao L,Wang S,Xu M,He Y,Zhang X,Xiong Y,Sun H,Ding H,Geng W,Shang H,Liang G

PA1-987 was used in Western Blot to report the mechanisms behind HIV-1 accessory protein, Vpr, enhancement of macrophage infection.

Thu Jun 17 00:00:00 EDT 2021

Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins.

Frontiers in neurology

Jiang L,Zhao J,Cheng JX,Wolozin B

PA1-987 was used in Western Blotting to explore the actions of two distinct types of tau aggregates, tau oligomers and tau fibrils in primary neuron cultures expressing human 4R0N tau.

Fri Jun 04 00:00:00 EDT 2021

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.

Cell death & disease

Huangfu J,Hao C,Wei Z,Wormstone IM,Yan H,Fan X

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Fri Apr 09 00:00:00 EDT 2021

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.

Cell death & disease

Huangfu J,Hao C,Wei Z,Wormstone IM,Yan H,Fan X

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Fri Apr 09 00:00:00 EDT 2021

Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.

DNA and cell biology

Cruz A,Ferian A,Alves PKN,Silva WJ,Bento MR,Gasch A,Labeit S,Moriscot AS

PA1-987 was used in Western Blotting to study the impact of leucine supplementation on myostatin expression using male rats.

Mon Nov 02 00:00:00 EST 2020

lncRNA ZEB1-AS1 Mediates Oxidative Low-Density Lipoprotein-Mediated Endothelial Cells Injury by Post-transcriptional Stabilization of NOD2.

Frontiers in pharmacology

Xu X,Ma C,Duan Z,Du Y,Liu C

PA1-987 was used in Western Blotting to analyse a poorly characterised human long non-coding RNA, ZEB1 antisense 1.

Thu Oct 01 00:00:00 EDT 2020

Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newly Diagnosed Epilepsy.

Frontiers in neuroscience

Lin Z,Gu Y,Zhou R,Wang M,Guo Y,Chen Y,Ma J,Xiao F,Wang X,Tian X

PA1-987 was used in Western Blotting to investigate the use of exosomal proteins as biomarkers for epilepsy.

Mon Sep 28 00:00:00 EDT 2020

miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock.

Scientific reports

Wu F,Wang JY,Chao W,Sims C,Kozar RA

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Fri Sep 25 00:00:00 EDT 2020

miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock.

Scientific reports

Wu F,Wang JY,Chao W,Sims C,Kozar RA

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Fri Sep 25 00:00:00 EDT 2020

Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma.

Cancers

Zhai Z,Samson JM,Yamauchi T,Vaddi PK,Matsumoto Y,Dinarello CA,Ravindran Menon D,Fujita M

PA1-987 was used in Western Blotting to investigate the role of inflammasome sensor NLRP1 in acquired drug resistance to temozolomide (TMZ) in melanoma.

Fri Sep 04 00:00:00 EDT 2020

S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson's disease.

PloS one

Wu W,Sung CC,Yu P,Li J,Chung KKK

PA1-987 was used in Western Blotting to demonstrate that GRK6 and CK2α can be S-nitrosylated by nitric oxide (NO) both in vitro and in vivo.

Mon Jul 20 00:00:00 EDT 2020

Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40.

American journal of physiology. Endocrinology and metabolism

Zhang L,Chen Z,Wang Y,Tweardy DJ,Mitch WE

PA1-987 was used in Western Blot to conclude that Stat3 activation in muscle increases IR in mice.

Fri May 01 00:00:00 EDT 2020

RNA Sequence Analyses throughout the Course of Mouse Cardiac Laminopathy Identify Differentially Expressed Genes for Cell Cycle Control and Mitochondrial Function.

Scientific reports

Shao Z,Koh W,Ni Y,Li W,Agatisa-Boyle B,Merkurjev D,Tang WHW

PA1-987 was used in Western Blotting to demonstrate that impaired oxidative phosphorylation takes place at the early disease stage and worsens with disease progression in familial dilated cardiomyopathy.

Mon Apr 20 00:00:00 EDT 2020

miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1.

Oncology reports

Lin J,Shen J,Yue H,Cao Z

PA1-987 was used in Western Blotting to identify that the downregulation of TPM1 and deactivation of the Bcl-2/P53 signaling pathways by miR-183-5p.1, promotes proliferation, migration and invasion in gastric cancer.

Sun Dec 01 00:00:00 EST 2019

Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent.

Molecules (Basel, Switzerland)

Hackler L,Gyuris M,Huzián O,Alföldi R,Szebeni GJ,Madácsi R,Knapp L,Kanizsai I,Puskás LG

PA1-987 was used in Western Blotting to show that the enantiomers of Q134 showed potent and similar activity in all tested assays.

Sat Nov 23 00:00:00 EST 2019

Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.

mBio

Winstel V,Schneewind O,Missiakas D

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Tue Nov 12 00:00:00 EST 2019

lncRNA ZEB1-AS1 promotes migration and metastasis of bladder cancer cells by post-transcriptional activation of ZEB1.

International journal of molecular medicine

Zhao X,Wang D,Ding Y,Zhou J,Liu G,Ji Z

PA1-987 was used in Western Blotting to determine the role of zinc finger E-box binding homeobox 1-antisense in bladder cancer progression and metastasis.

Mon Jul 01 00:00:00 EDT 2019

Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer.

Oncology letters

Nolasco-Quiroga M,Rosas-Díaz M,Moreno J,Godínez-Aguilar R,López-Ibarra MJ,Piña-Sánchez P,Alvarado-Cabrero I,Vázquez-Gómez G,Rocha-Zavaleta L,Arenas-Aranda D,Salamanca-Gómez F

PA1-987 was used in Western Blotting to analyse the expression level of focal adhesion kinase isoforms in ovarian cancer.

Sat Jun 01 00:00:00 EDT 2019

lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma.

International journal of oncology

Chen F,Qi S,Zhang X,Wu J,Yang X,Wang R

PA1-987 was used in Western Blotting to investigate the regulatory model of the long noncoding RNA placenta-specific protein 2 upregulation in oral squamous cell carcinoma, and its function in OSCC malignant progression.

Mon Apr 01 00:00:00 EDT 2019

Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening.

Scientific reports

Martin DDO,Kanuparthi PS,Holland SM,Sanders SS,Jeong HK,Einarson MB,Jacobson MA,Thomas GM

PA1-987 was used in Western Blotting to report that DLK subcellular localization in non-neuronal cells is highly palmitoylation-dependent and can thus serve as a proxy readout to identify inhibitors of DLK palmitoylation by High Content Screening.

Wed Mar 06 00:00:00 EST 2019

Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer.

Molecular cancer

Dong H,Hu J,Zou K,Ye M,Chen Y,Wu C,Chen X,Han M

PA1-987 was used in Western Blotting to identify the regulatory role of long non-coding RNA in trastuzumab resistance and accompanied Epithelial-mesenchymal Transition process in advanced human epidermal growth factor receptor 2-positive breast cancer.

Tue Jan 08 00:00:00 EST 2019

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines.

Virulence

Liu J,Ma'ayeh S,Peirasmaki D,Lundström-Stadelmann B,Hellman L,Svärd SG

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Mon Dec 31 00:00:00 EST 2018

Exploration of the regulation and control mechanisms of miR-145 in trophoblast cell proliferation and invasion.

Experimental and therapeutic medicine

Chi Z,Zhang M

PA1-987 was used in Western Blotting to investigate the functions of miR-145 in preeclampsia.

Sat Dec 01 00:00:00 EST 2018

Transgenic overexpression of furin increases epileptic susceptibility.

Cell death & disease

Yang Y,He M,Tian X,Guo Y,Liu F,Li Y,Zhang H,Lu X,Xu D,Zhou R,Ma Y,Wang W,Chen G,Hu Y,Wang X

PA1-987 was used in Western Blotting to study the role of furin expression in epilepsy.

Wed Oct 17 00:00:00 EDT 2018

Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose-phosphate pathways in embryonic heart.

The Journal of biological chemistry

Peoples JNR,Maxmillian T,Le Q,Nadtochiy SM,Brookes PS,Porter GA,Davidson VL,Ebert SN

PA1-987 was used in Western Blotting to study the effects of adrenergic hormones on metabolism in the embryonic heart.

Fri May 04 00:00:00 EDT 2018

Rapid estrogen receptor-α signaling mediated by ERK activation regulates vascular tone in male and ovary-intact female mice.

American journal of physiology. Heart and circulatory physiology

Kim SC,Boese AC,Moore MH,Cleland RM,Chang L,Delafontaine P,Yin KJ,Lee JP,Hamblin MH

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Thu Feb 01 00:00:00 EST 2018

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.

Cancer cell

Guler GD,Tindell CA,Pitti R,Wilson C,Nichols K,KaiWai Cheung T,Kim HJ,Wongchenko M,Yan Y,Haley B,Cuellar T,Webster J,Alag N,Hegde G,Jackson E,Nance TL,Giresi PG,Chen KB,Liu J,Jhunjhunwala S,Settleman J,Stephan JP,Arnott D,Classon M

PA1-987 was used in Western Blotting to show that the genomes of a cancer cell subpopulation that survives treatment with otherwise lethal drugs, the drug-tolerant persisters, exhibit a repressed chromatin state.

Mon Aug 14 00:00:00 EDT 2017

Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.

Molecular medicine reports

Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H

PA1-987 was used in Western Blotting to investigate the effects and underlying mechanism of chlorogenic acid on IL-1Β-induced osteoarthritis chondrocytes.

Tue Aug 01 00:00:00 EDT 2017

Impact of R264C and R264H polymorphisms in human aromatase function.

The Journal of steroid biochemistry and molecular biology

Baravalle R,Di Nardo G,Bandino A,Barone I,Catalano S,Andò S,Gilardi G

PA1987 was used in western blot to characterize cytochrome P450 aromatase mutations

Wed Mar 01 00:00:00 EST 2017

Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer.

Nucleic acids research

Wagner S,Herrmannová A,Šikrová D,Valášek LS

Published figure using GAPDH polyclonal antibody (Product # PA1-987) in Western Blot

Thu Dec 15 00:00:00 EST 2016

Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering.

Biomedical materials (Bristol, England)

Jain S,Krishna Meka SR,Chatterjee K

PA1987 was used in western blot to create curcumin-eluting tissue scaffolds and explore their potential in bone tissue regeneration

Thu Oct 06 00:00:00 EDT 2016

Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth.

Biology of reproduction

Nadeau-Vallée M,Boudreault A,Leimert K,Hou X,Obari D,Madaan A,Rouget R,Zhu T,Belarbi L,Brien MÈ,Beaudry-Richard A,Olson DM,Girard S,Chemtob S

PA1987 was used in western blot to measure the expression and function of neuromedin U receptor 2 and its ligands in gestational tissues

Thu Sep 01 00:00:00 EDT 2016

The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator.

British journal of pharmacology

Hyrsova L,Smutny T,Carazo A,Moravcik S,Mandikova J,Trejtnar F,Gerbal-Chaloin S,Pavek P

PA1-987 was used in western blot to study down-regulation of organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator by the pregane X receptor

Sun May 01 00:00:00 EDT 2016

DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.

Developmental biology

Ajima R,Bisson JA,Helt JC,Nakaya MA,Habas R,Tessarollo L,He X,Morrisey EE,Yamaguchi TP,Cohen ED

PA1-987 was used in Western Blotting to investigate the Wnt-associated pathways induced by DAAM1 and DAAM2 in the myocardium.

Tue Dec 01 00:00:00 EST 2015

An animal model for chorioamnionitis at term.

American journal of obstetrics and gynecology

Dell'Ovo V,Rosenzweig J,Burd I,Merabova N,Darbinian N,Goetzl L

PA1-987 was used in western blot to develop an animal model for intrapartum inflammation at term.

Tue Sep 01 00:00:00 EDT 2015

Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.

Developmental biology

Bisson JA,Mills B,Paul Helt JC,Zwaka TP,Cohen ED

PA1-987 was used in western blot to study the regulation of the canonical Wnt pathway and its effect on cardiac progenitor development

Sun Feb 01 00:00:00 EST 2015

Intestinal fatty acid binding protein (fabp2) in Atlantic salmon (Salmo salar): Localization and alteration of expression during development of diet induced enteritis.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

Venold FF,Penn MH,Thorsen J,Gu J,Kortner TM,Krogdahl A,Bakke AM

PA1-987 was used in western blot to study the expression of intestinal fatty acid binding proteins FABP2a1, FABP2a2 and FABPb during diet-induced enteritis in Atlantic salmon

Tue Jan 01 00:00:00 EST 2013

Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure.

The Journal of physiology

Briston SJ,Caldwell JL,Horn MA,Clarke JD,Richards MA,Greensmith DJ,Graham HK,Hall MC,Eisner DA,Dibb KM,Trafford AW

PA1-987 was used in western blot to study the mechanism for the dysfunctional excitation-contraction coupling in heart failure

Tue Mar 15 00:00:00 EDT 2011

An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Asundi J,Reed C,Arca J,McCutcheon K,Ferrando R,Clark S,Luis E,Tien J,Firestein R,Polakis P

PA1-987 was used in western blot to evaluate an antibody-drug conjugate for melanoma treatment

Tue Mar 01 00:00:00 EST 2011

Bioinformatics

Protein Aliases: 38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; GAPDH; GAPDH-2; Glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase type 2; Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; HGNC:4141; MGC88685; Peptidyl-cysteine S-nitrosylase GAPDH; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase

Gene Aliases: BARS-38; CDABP0047; G3PD; GAPD; Gapd-s; GAPD2; GAPDH; GAPDH-2; GAPDH2; GAPDHS; GAPDS; HEL-S-162eP; HEL-S-278; HSD-35; HSD35; OK/SW-cl.12

UniProt ID: (Human) P04406, (Human) O14556, (Mouse) Q3UMT2, (Rat) P04797, (Rat) Q9ESV6, (Mouse) Q64467

Entrez Gene ID: (Human) 2597, (Dog) 403755, (Human) 26330, (Dog) 476483, (Mouse) 14433, (Rat) 24383, (Rat) 66020, (Mouse) 14447

Molecular Function: dehydrogenase