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Product Details
H00002617-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GARS (ENSP00000373918, 1 a.a. approximately 685 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Sequence of this protein is as follows: MDGAGAEEVL APLRLAVRQQ GDLVRKLKED KAPQVDVDKA VAELKARKRV LEAKELALQP KDDIVDRAKM EDTLKRRFFY DQAFAIYGGV SGLYDFGPVG CALKNNIIQT WRQHFIQEEQ ILEIDCTMLT PEPVLKTSGH VDKFADFMVK DVKNGECFRA DHLLKAHLQK LMSDKKCSVE KKSEMESVLA QLDNYGQQEL ADLFVNYNVK SPITGNDLSP PVSFNLMFKT FIGPGGNMPG YLRPETAQGI FLNFKRLLEF NQGKLPFAAA QIGNSFRNEI SPRSGLIRVR EFTMAEIEHF VDPSEKDHPK FQNVADLHLY LYSAKAQVSG QSARKMRLGD AVEQGVINNT VLGYFIGRIY LYLTKVGISP DKLRFRQHME NEMAHYACDC WDAESKTSYG WIEIVGCADR SCYDLSCHAR ATKVPLVAEK PLKEPKTVNV VQFEPSKGAI GKAYKKDAKL VMEYLAICDE CYITEMEMLL NEKGEFTIET EGKTFQLTKD MINVKRFQKT LYVEEVVPNV IEPSFGLGRI MYTVFEHTFH VREGDEQRTF FSFPAVVAPF KCSVLPLSQN QEFMPFVKEL SEALTRHGVS HKVDDSSGSI GRRYARTDEI GVAFGVTIDF DTVNKTPHTA TLRDRDSMRQ IRAEISELPS IVQDLANGNI TWADVEARYP LFEGQETGKK ETIEE
Target Information
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6.1.1.14; AP-4-A synthetase; Ap4A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; Diadenosine tetraphosphate synthetase; EC 2.1.2.29; GARTF; glycine tRNA ligase; Glycine--tRNA ligase; Glycyl-tRNA synthetase; Glycyl-tRNA synthetase 1; GlyRS; MGC47764; PAIS; PGFT; PRGS
Gene Aliases: CMT2D; DSMAV; GARS; GARS1; GlyRS; HMN5; SMAD1
UniProt ID: (Human) P41250
Entrez Gene ID: (Human) 2617
Molecular Function:
aminoacyl-tRNA synthetase
translational protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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