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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 319 and 554 of Human GARS|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30038 targets GARS in WB applications and shows reactivity with Human samples.
The PA5-30038 immunogen is recombinant fragment corresponding to a region within amino acids 319 and 554 of Human GARS.
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AP-4-A synthetase; Charcot-Marie-Tooth neuropathy; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; CMT2D; D; diadenosine tetraphosphate synthetase; DSMAV; glycine tRNA ligase; glycine--tRNA ligase; GlyRS; HMN5; neuronal type; SMAD1
CMT2D; DSMAV; GARS; GlyRS; HMN5; SMAD1