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Product Details
17903-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GAS1 Fusion Protein Ag12275 (28-345 aa encoded by BC074908)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LQLLGSAPR GSGLAHGRRL ICWQALLQCQ GEPECSYAYN QYAEACAPVL AQHGGGDAPG AAAAAFPASA ASFSSRWRCP SHCISALIQL NHTRRGPALE DCDCAQDENC KSTKRAIEPC LPRTSGGGAG GPGAGGVMGC TEARRRCDRD SRCNLALSRY LTYCGKVFNG LRCTDECRTV IEDMLAMPKA ALLNDCVCDG LERPICESVK ENMARLCFGA ELGNGPGSSG SDGGLDDYYD EDYDDEQRTG GAGGEQPLDD DDGVPHPPRP GSGAAASGGR GDLPYGPGRR SSGGGGRLAP RGAWTPLASI LLLLLGPLF (28-345 aa encoded by BC074908)
Target Information
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GAS-1; growth arrest-specific 1; Growth arrest-specific gene-1; Growth arrest-specific protein 1
Gene Aliases: AW554192; Gas-1; GAS1
UniProt ID: (Human) P54826, (Mouse) Q01721
Entrez Gene ID: (Human) 2619, (Mouse) 14451
cell cycle arrest
regulation of smoothened signaling pathway
negative regulation of protein processing
cellular response to vascular endothelial growth factor stimulus
regulation of apoptotic process
cell fate commitment
negative regulation of mitotic cell cycle
developmental growth
regulation of ER to Golgi vesicle-mediated transport
positive regulation of mesenchymal cell proliferation
cell cycle
axon guidance
positive regulation of cell proliferation
dorsal/ventral pattern formation
programmed cell death
cerebellum morphogenesis
dorsal/ventral neural tube patterning
negative regulation of cell growth
outer ear morphogenesis
middle ear morphogenesis
odontogenesis
embryonic digit morphogenesis
camera-type eye development
negative regulation of apoptotic process
negative regulation of smoothened signaling pathway
positive regulation of smoothened signaling pathway
eye morphogenesis
embryonic morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system development
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
palate development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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