|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 203 of GAS41 (Uniprot ID#O95619)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34867 targets GAS41 in ICC, IF, and WB applications and shows reactivity with Human samples.
The PA5-34867 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 203 of GAS41 (Uniprot ID#O95619).
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4930573H17Rik; B230215M10Rik; GAS41; Glioma-amplified sequence 41; glioma-amplified sequence-41; NUBI-1; nuBI1; NuMA binding protein 1; NuMA-binding protein 1; YAF9; YEATS domain-containing protein 4
Gene Aliases: 4930573H17Rik; B230215M10Rik; GAS41; NUBI-1; YAF9; YEATS4
UniProt ID: (Human) O95619
Entrez Gene ID: (Human) 8089
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