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Invitrogen

GAS6 Polyclonal Antibody

View all (12) GAS6 antibodies

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Product Details

PA5-121208

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein (or fragment)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.69 mg/mL

Amount

369 µg

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2914780

Product Specific Information

Positive test controls include: HeLa, NCI-H460, HT-1080, SW620, DU145. The target is usually found in the following locations: Secreted.

Target Information

This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AXL receptor tyrosine kinase ligand; AXL stimulatory factor; GAS 6; GAS-6; Growth arrest-specific protein 6; unnamed protein product

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Gene Aliases: AXLLG; AXSF; Gas-6; GAS6

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UniProt ID: (Human) Q14393, (Mouse) Q61592

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Entrez Gene ID: (Human) 2621, (Mouse) 14456

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Function(s)
phosphatidylserine binding receptor binding calcium ion binding protein binding protein binding, bridging receptor tyrosine kinase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process metal ion binding receptor agonist activity voltage-gated calcium channel activity protein tyrosine kinase activator activity binding, bridging extracellular matrix protein
Process(es)
neuron migration positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of glomerular filtration protein phosphorylation phagocytosis apoptotic process signal transduction cell surface receptor signaling pathway enzyme linked receptor protein signaling pathway blood coagulation cellular response to starvation positive regulation of gene expression negative regulation of tumor necrosis factor-mediated signaling pathway cell migration fusion of virus membrane with host plasma membrane viral genome replication cell differentiation organ regeneration cell-substrate adhesion cellular response to nutrient levels positive regulation of TOR signaling activation of protein kinase B activity negative regulation of interferon-gamma production negative regulation of interleukin-1 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of natural killer cell differentiation myeloid cell apoptotic process negative regulation of myeloid cell apoptotic process cellular response to interferon-alpha B cell chemotaxis negative regulation of apoptotic process apoptotic cell clearance fibroblast apoptotic process positive regulation of protein kinase activity negative regulation of transcription, DNA-templated viral entry into host cell receptor-mediated virion attachment to host cell positive regulation of protein export from nucleus positive regulation of fibroblast proliferation positive regulation of phagocytosis positive regulation of protein kinase B signaling negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport cellular response to vitamin K cellular response to glucose stimulus cellular response to growth factor stimulus cellular response to xenobiotic stimulus protein localization to plasma membrane extracellular matrix assembly dendritic cell differentiation hematopoietic stem cell migration to bone marrow negative regulation of oligodendrocyte apoptotic process negative regulation of fibroblast apoptotic process negative regulation of endothelial cell apoptotic process positive regulation of dendritic cell chemotaxis negative regulation of renal albumin absorption negative regulation of dendritic cell apoptotic process macrophage cytokine production peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation negative regulation of protein import into nucleus, translocation regulation of ion transmembrane transport cellular response to drug regulation of growth negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of sequence-specific DNA binding transcription factor activity protein kinase B signaling negative regulation of interleukin-1 secretion positive regulation of protein tyrosine kinase activity protein targeting to plasma membrane negative regulation of interleukin-6 secretion positive regulation of receptor activity
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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