Active Motif

GATA-6 Polyclonal Antibody

View all (10) GATA6 antibodies

Questions & Answers

Questions & Answers

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GATA-6 Antibody in Immunocytochemistry (ICC/IF) — GATA-6 antibody (pAb) tested by Immunofluorescence. Formaldehyde fixed HeLa cells stained with GATA-6 antibody at a 1:2,000 dilution.

GATA-6 Antibody in Western Blot (WB) — GATA-6 antibody (pAb) tested by Western blot. Nuclear extract (20 µg) of SW48 cells probed with GATA-6 antibody at a dilution of 1:500.

Product Details

61063

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500	-
Immunocytochemistry (ICC/IF)	1:2,000	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	This GATA-6 antibody was raised against a peptide within the N-terminus of human GATA-6. View antigen
Conjugate	Unconjugated
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	70mM tris, pH 8, with 30% glycerol, 31mM glycine, 105mM NaCl, 0.07mM EDTA
Contains	0.035% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2793493

Target Information

GATA6 is thought to be important for regulating terminal differentiation and/or proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ASD9; AVSD5; GATA-binding factor 6; Transcription factor GATA-6

Gene Aliases: GATA6

UniProt ID: (Human) Q92908

Entrez Gene ID: (Human) 2627

Molecular Function: DNA-binding transcription factor

negative regulation of transcription from RNA polymerase II promoter in utero embryonic development liver development outflow tract septum morphogenesis type B pancreatic cell differentiation pancreatic A cell differentiation transcription from RNA polymerase II promoter phospholipid metabolic process endodermal cell fate determination blood coagulation male gonad development cardiac muscle hypertrophy in response to stress positive regulation of BMP signaling pathway negative regulation of transforming growth factor beta1 production negative regulation of transforming growth factor beta2 production tube morphogenesis response to drug negative regulation of apoptotic process response to estrogen cellular protein metabolic process cell fate commitment positive regulation of angiogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell development organ formation smooth muscle cell differentiation positive regulation of cardioblast differentiation cardiac muscle cell differentiation positive regulation of cardiac muscle cell proliferation lung saccule development Clara cell differentiation Type II pneumocyte differentiation intestinal epithelial cell differentiation cardiac vascular smooth muscle cell differentiation response to growth factor positive regulation of cell cycle arrest cellular response to gonadotropin stimulus cellular response to hypoxia cellular response to BMP stimulus

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding zinc ion binding protein kinase binding transcription regulatory region DNA binding