PA1-099 specifically detects GATA1 and does not cross-react with GATA2 or GATA3.
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
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Protein Aliases: ERYF1; Erythroid transcription factor; erythroid transcription factor 1; erythrold transcription factor 1; GATA binding protein 1; GATA binding protein 1 (globin transcription factor 1); GATA-1; GATA-binding factor 1; GATA-binding protein 1; GATA-binding protein 1 (globin transcription factor 1); GATA1; GF1; globin transcription factor 1; HGNC:4170; NF-E1 DNA-binding protein; NFE1; nuclear factor, erythroid 1; transcription factor GATA1; XLTT
Gene Aliases: ERYF1; GATA-1; GATA1; GF-1; GF1; NF-E1; NFE1; XLANP; XLTDA; XLTT