Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:100-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:1,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein fragment corresponding to a region within amino acids 130 and 397 of Human GATA2 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.38 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 1% BSA, 20% glycerol |
Contains |
0.025% ProClin 300 |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2547210 |
Recommended positive controls: A549, HeLa, HepG2, HCT116, H1299.
Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (87%), Pig (99%), Chicken (86%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endothelial transcription factor GATA-2; FLJ45948; GATA-binding protein 2; GATA-bindning protein 2; gata2 {ECO:0000312|EMBL:AAK51128.1}; MGC2306
Gene Aliases: DCML; Gata-2; GATA2; IMD21; MONOMAC; NFE1B
UniProt ID: (Human) P23769, (Mouse) O09100, (Rat) Q924Y4
Entrez Gene ID: (Human) 2624, (Mouse) 14461, (Rat) 25159
Molecular Function:
DNA-binding transcription factor
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