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Proteintech
GATA5 Polyclonal Antibody
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Product Details
55433-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Amount
103.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
GATA binding factor 5 is a transcription regulator involved in embryonic development. In addition, the protein encoded by this gene contains two GATA-type zinc fingers and is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha). This interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. GATA-5 may be involved in the establishment of cardiac smooth muscle cell diversity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GATA binding factor-5; GATA-binding factor 5; GATA-binding protein 5; Transcription factor GATA-5; Transcription factor GATA-5 (GATA binding factor-5)
Gene Aliases: bB379O24.1; CHTD5; GATA5; GATAS
UniProt ID: (Human) Q9BWX5, (Mouse) P97489
Entrez Gene ID: (Human) 140628, (Mouse) 14464
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription regulatory region DNA binding
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
heart induction
aortic valve morphogenesis
endocardial cushion fusion
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
heart development
anatomical structure morphogenesis
tissue development
negative regulation of cardiac muscle hypertrophy
positive regulation of gene expression
negative regulation of gene expression
cell differentiation
cell fate commitment
positive regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle tissue development
intestinal epithelial cell differentiation
positive regulation of cardiac endothelial to mesenchymal transition
cellular response to hydrogen peroxide
cellular response to nitric oxide
cellular response to BMP stimulus
positive regulation of apoptotic DNA fragmentation
transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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