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GATA binding factor 5 is a transcription regulator involved in embryonic development. In addition, the protein encoded by this gene contains two GATA-type zinc fingers and is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha). This interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. GATA-5 may be involved in the establishment of cardiac smooth muscle cell diversity.
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Protein Aliases: GATA binding factor-5; GATA-binding factor 5; GATA-binding protein 5; Transcription factor GATA-5; Transcription factor GATA-5 (GATA binding factor-5)
Gene Aliases: bB379O24.1; GATA5; GATAS
Molecular Function: DNA-binding transcription factor