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GATA6 Polyclonal Antibody

View all (10) GATA6 antibodies

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GATA6 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using (Product # 55435-1-AP) (GATA6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

GATA6 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 55435-1-AP (GATA6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

GATA6 Antibody in Western Blot (WB) — BxPC-3 cells were subjected to SDS PAGE followed by western blot with 55435-1-AP (GATA6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

GATA6 Antibody in Western Blot (WB) — MCF7 cells were subjected to SDS PAGE followed by western blot with 55435-1-AP (GATA6 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

55435-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:200	-

Product Specifications
Species Reactivity	Human, Mouse
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide
Conjugate	Unconjugated
Form	Liquid
Concentration	0.35 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Target Information

GATA6 is thought to be important for regulating terminal differentiation and/or proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Xiang C,Wang J,Kou X,Chen X,Qin Z,Jiang Y,Sun C,Xu J,Tan W,Jin L,Lin D,He F,Wang H

Fri May 01 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: ASD9; AVSD5; GATA-binding factor 6; GATA-binding protein 6; Transcription factor GATA-6

Gene Aliases: AA410133; GATA-6; GATA6

UniProt ID: (Human) Q92908, (Mouse) Q61169

Entrez Gene ID: (Human) 2627, (Mouse) 14465

Molecular Function: DNA-binding transcription factor

negative regulation of transcription from RNA polymerase II promoter in utero embryonic development liver development outflow tract septum morphogenesis type B pancreatic cell differentiation pancreatic A cell differentiation transcription from RNA polymerase II promoter phospholipid metabolic process endodermal cell fate determination blood coagulation male gonad development cardiac muscle hypertrophy in response to stress positive regulation of BMP signaling pathway negative regulation of transforming growth factor beta1 production negative regulation of transforming growth factor beta2 production tube morphogenesis response to drug negative regulation of apoptotic process response to estrogen cellular protein metabolic process cell fate commitment positive regulation of angiogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell development organ formation smooth muscle cell differentiation positive regulation of cardioblast differentiation cardiac muscle cell differentiation positive regulation of cardiac muscle cell proliferation lung saccule development Clara cell differentiation Type II pneumocyte differentiation intestinal epithelial cell differentiation cardiac vascular smooth muscle cell differentiation response to growth factor positive regulation of cell cycle arrest cellular response to gonadotropin stimulus cellular response to hypoxia cellular response to BMP stimulus transcription, DNA-templated regulation of transcription, DNA-templated regulation of gene expression epithelial cell differentiation pancreas development endodermal cell differentiation positive regulation of apoptotic process positive regulation of transcription, DNA-templated cardiac muscle tissue development

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding zinc ion binding protein kinase binding transcription regulatory region DNA binding enhancer sequence-specific DNA binding DNA binding double-stranded DNA binding sequence-specific DNA binding metal ion binding