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Invitrogen
GATAD2B Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
GATAD2B Antibody (PA5-53536) in WB
Western blot analysis of GATAD2B in SK-BR-3 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using a GATAD2B Polyclonal Antibody (Product # PA5-53536). Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Product Details
PA5-53536
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GATAD2B
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641884
Product Specific Information
Immunogen sequence: NLEVPHELPT KQDGSGVKGY EEKLNGNLRP HGDNRTAGRP GKENINDEPV DMSARRSEPE RGRLTPSPDI IVLSDNEASS PRSSSRMEER LKAANLEMFK GKGIEERQQL IKQLRDELRL EEARLV
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GATA zinc finger domain-containing protein 2B; p66/p68; transcription repressor p66 beta component of the MeCP1 complex; transcription repressor p66 component of the MeCP1 complex; Transcriptional repressor p66-beta
Gene Aliases: AL118180; C430014D17Rik; GATAD2B; KIAA1150; mKIAA1150; MRD18; P66beta; p68; RGD1308533
UniProt ID: (Human) Q8WXI9, (Mouse) Q8VHR5
Entrez Gene ID: (Human) 57459, (Rat) 310614, (Mouse) 229542
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
nucleosomal DNA binding
sequence-specific DNA binding
metal ion binding
DNA-binding transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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