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| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
GBA Fusion Protein Ag13981 (1-221 aa encoded by BC000349) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.33 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MCLQPLQEQ KQWALDGAEY RTIQANCTGT GIGYNIIWVP MASCDFSIRT YTYADTPDDF QLHNFSLPEE DTKLKIPLIH RALQLAQRPV SLLASPWTSP TRLKTKGAGN GKGPLKGQPR DIYHQTWARY IVKFLDAYAE HKLQFWAVTA ENEPSAGLLS GYPFQCLGFT PEHQRDFIAR DLGPTLANGT HHNVRLLMLD DQRLLLPHWA KVVLTDPEAA KG (1-221 aa encoded by BC000349)
GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acid beta-glucosidase; Alglucerase; Beta-GC; Beta-glucocerebrosidase; Cholesterol glucosyltransferase; Cholesteryl-beta-glucosidase; D-glucosyl-N-acylsphingosine glucohydrolase; glucosidase, beta, acid; glucosylceramidase-like protein; Imiglucerase; Lysosomal acid GCase; Lysosomal acid glucosylceramidase; lysosomal glucocerebrosidase; SGTase
Gene Aliases: GBA; GBA1; GC; GCB; GLUC
UniProt ID: (Human) P04062
Entrez Gene ID: (Human) 2629
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