Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 10 publications 10 publications |
Immunohistochemistry (IHC) |
- | View 3 publications 3 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | View 4 publications 4 publications |
Flow Cytometry (Flow) |
0.2 µg/1x10^6 cells | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
GBP5 Fusion Protein Ag4103 (382-586 aa encoded by BC031639) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.43 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: LETLLDAKQ NDICKRNLEA SSDYCSALLK DIFGPLEEAV KQGIYSKPGG HNLFIQKTEE LKAKYYREPR KGIQAEEVLQ KYLKSKESVS HAILQTDQAL TETEKKKKEA QVKAEAEKAE AQRLAAIQRQ NEQMMQERER LHQEQVRQME IAKQNWLAEQ QKMQEQQMQE QAAQLSTTFQ AQNRSLLSEL QHAQRTVNND DPCVLL (382-586 aa encoded by BC031639)
The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GBP-5; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; Guanylate-binding protein 5
Gene Aliases: GBP-5; GBP5; UNQ2427/PRO4987
UniProt ID: (Human) Q96PP8
Entrez Gene ID: (Human) 115362
Molecular Function:
heterotrimeric G-protein
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