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Product Details
GCDH-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids within region 200-250 on Human GCDH/GCD protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer with 20% glycerol, 0.5% BSA
Contains
0.01% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Quantity: 100 µg IgG per vial
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GCD; Glutaryl-CoA dehydrogenase, mitochondrial; glutaryl-Coenzyme A dehydrogenase
Gene Aliases: 9030411L18; ACAD5; AI266902; D17825; GCD; GCDH
UniProt ID: (Human) Q92947, (Mouse) Q60759
Entrez Gene ID: (Human) 2639, (Mouse) 270076, (Rat) 364975
fatty-acyl-CoA binding
glutaryl-CoA dehydrogenase activity
electron carrier activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
acyl-CoA dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
Performance Guarantee
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