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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 775 and 837 of Human GCN5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27146 targets GCN5 in WB applications and shows reactivity with Human samples.
The PA5-27146 immunogen is synthetic peptide corresponding to a region within amino acids 775 and 837 of Human GCN5.
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GCN5; GCN5 (general control of amino-acid synthesis; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5L2; General control of amino acid synthesis; General control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase K; Histone acetyltransferase KAT2A; homolog)-like 2; homolog-like 2; HsGCN5; K(lysine) acetyltransferase 2A; Lysine acetyltransferase 2A; PCAF-b; STAF97; yeast
GCN5; GCN5L2; HGCN5; KAT2A; PCAF-b