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GCNT1 Antibody (PA5-12145) in IHC (P)
Immunohistochemistry analysis of GCNT1 in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with GCNT1 polyclonal antibody (Product # PA5-12145) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepa... View More
Product Details
PA5-12145
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 88-117 amino acids from the central region of human GCNT1
Conjugate
Form
Liquid
Concentration
2.0 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2278769
Target Information
Glycosylation is one of the most universal but at the same time complex protein modifications. Modification with sugar moeties can be both co- translational and post- translational, occurring in the endoplasmatic reticulum and golgi. Three different forms of glycosylation can be distinguished: N-linked oligosaccharides, O-linked oligosaccharides and glycosyl- phosphatidylinositol (GPI-) anchors. Glycosylation results in thousands of distinct, bioactive glycoproteins resident throughout the cell that strongly determine protein-protein, carbohydrate-protein, membrane, and adhesion properties. Diseases associated with glycosylation defects include Congenital disorders of glycosylation, (CDG), also known as carbohydrate deficient glycoprotein syndromes, and diseases associated with advanced aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT); beta-1,6-N-acetylglucosaminyltransferase; C2GlcNAcT; C2GNT; C2GnT-L; Core 2 beta-1,6-N-acetylglucosaminyltransferase; core 2 beta-1,6-N-acetylglucosaminyltransferase I; core 2 beta1,6 N-acetylglucosaminyltransferase-I; core 2 branching enzyme; core 2 GnT; Core 2-branching enzyme; Core2-GlcNAc-transferase; glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase); Leukocyte type core 2 beta-1,6-N-acetylglucosaminyltransferase
Gene Aliases: 5630400D21Rik; B130048E03; C2 GlcNAcT; C2GNT; C2GNT-L; C2GNT1; G6NT; GCNT1; IGnT; NACGT2; NAGCT2
UniProt ID: (Human) Q02742, (Mouse) Q09324
Entrez Gene ID: (Human) 2650, (Mouse) 14537
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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