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Invitrogen
GCP2 Polyclonal Antibody
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Product Details
PA5-75797
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human TUBGCP2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The γ-Tubulin complex is composed of γ Tubulin and the γ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. γ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubulin complex. GCP2 (γ-Tubulin complex component 2), also known as TUBGCP2 or SPBC97 (spindle pole body protein Spc97 homolog) is a ubiquitously expressed 902 amino acid protein that localizes to the centrosome and is involved in microtubule nucleation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloprotease domain 8; Gamma-ring complex protein 103 kDa; Gamma-tubulin complex component 2; GCP-2; h103p; hGrip103; hSpc97; Spindle pole body protein Spc97 homolog; tubulin, gamma complex associated protein 2
Gene Aliases: 1700022B05Rik; Adam8; GCP-2; GCP2; Grip103; h103p; hGCP2; hSpc97; SPBC97; Spc97p; TUBGCP2
UniProt ID: (Human) Q9BSJ2, (Mouse) Q921G8
Entrez Gene ID: (Human) 10844, (Mouse) 74237, (Rat) 309098
protein complex assembly
microtubule nucleation
meiotic nuclear division
cytoplasmic microtubule organization
centrosome duplication
interphase microtubule nucleation by interphase microtubule organizing center
mitotic spindle assembly
microtubule cytoskeleton organization
biological_process
proteolysis
integrin-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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