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Invitrogen
GDI1 Polyclonal Antibody
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FIGURE: 1 / 6
GDI1 Antibody (71-0300) in WB
Western blot analysis was performed on membrane enriched extracts (30 µg lysate) of IMR32 (Lane 1), T98G (Lane 2), U-87 MG (Lane 3), SH-SY5Y (Lane 4) and HEK-293 (Lane 5).The blots were probed with GDI1 Rabbit polyclonal Antibody (Product # 71-0300, 2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A ~55 kDa band corresponding to GDI1 was observed across the cell lines tested. Known quantity of protein samples we... View More
Product Details
71-0300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
C. elegans,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 20 amino acid synthetic peptide derived from bovine brain Rab Guanine Nucleotide Dissociation Inhibitor (GDI).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GDI-1; GDP-dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 48; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDIalpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; SMG p25A GDI; testis secretory sperm-binding protein Li 208a
Gene Aliases: 1A; GDI1; GDIA; GDIalpha; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
UniProt ID: (Bovine) P21856, (Human) P31150, (Mouse) P50396, (Rat) P50398
Entrez Gene ID: (Bovine) 281188, (Human) 2664, (Mouse) 14567, (Rat) 25183
protein transport
Rab protein signal transduction
positive regulation of GTPase activity
negative regulation of axonogenesis
negative regulation of protein targeting to membrane
signal transduction
regulation of small GTPase mediated signal transduction
response to calcium ion
oxidation-reduction process
regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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