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Invitrogen
GDI1 Polyclonal Antibody
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FIGURE: 1 / 5
GDI1 Antibody (PA5-81504) in ICC/IF
Immunofluorescence staining of GDI1 in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with GDI1 Polyclonal Antibody (Product # PA5-81504, 1:1,000) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm.
Product Details
PA5-81504
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human GDI1
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human GDI1.
Target Information
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDI-1; GDI1; Guanosine diphosphate dissociation inhibitor 1; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; testis secretory sperm-binding protein Li 208a; unnamed protein product
Gene Aliases: 1A; GDI1; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4; XLID41
UniProt ID: (Human) P31150
Entrez Gene ID: (Human) 2664
ER to Golgi vesicle-mediated transport
Golgi to plasma membrane transport
signal transduction
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
Rab protein signal transduction
positive regulation of toll-like receptor signaling pathway
toll-like receptor 4 signaling pathway
positive regulation of axon extension
negative regulation of axonogenesis
response to calcium ion
negative regulation of protein targeting to membrane
negative regulation of cellular protein localization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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