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Proteintech
GDI2 Polyclonal Antibody
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Product Details
10116-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Monkey,
Mouse,
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GDI2 Fusion Protein Ag0170 (1-232 aa encoded by BC005145)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can bind both GDIs for the close sequences.
Immunogen sequence: MNEEYDVIV LGTGLTECIL SGIMSVNGKK VLHMDRNPYY GGESASITPL EDLYKRFKIP GSPPESMGRG RDWNVDLIPK FLMANGQLVK MLLYTEVTRY LDFKVTEGSF VYKGGKIYKV PSTEAEALAS SLMGLFEKRR FRKFLVYVAN FDEKDPRTFE GIDPKKTTMR DVYKKFDLGQ DVIDFTGHAL ALYRTDDYLD QPCYETINRI KLYSESLARY GKSPYLYPLY GLG (1-232 aa encoded by BC005145)
Target Information
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 46e; GDI beta; GDI-2; GDI-3; GDI2; guanosine diphosphate (GDP) dissociation inhibitor 3; Guanosine diphosphate dissociation inhibitor 2; guanosine diphosphate dissociation inhibitor 3; Rab GDI beta; Rab GDP dissociation inhibitor beta; RAB GDP dissociation inhibitor beta-2; rab GDP-dissociation inhibitor, beta; RabGDI beta; unnamed protein product
Gene Aliases: GDI-B; GDI2; Gdi3; GDIB; HEL-S-46e; RABGDIB
UniProt ID: (Human) P50395, (Mouse) Q61598, (Rat) P50399
Entrez Gene ID: (Human) 2665, (Mouse) 14569, (Rat) 29662
signal transduction
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
negative regulation of cilium assembly
negative regulation of protein localization to cilium
negative regulation of cellular protein localization
positive regulation of GTPase activity
regulation of catalytic activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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