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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GDI2 Antibodies

          Invitrogen

          GDI2 Polyclonal Antibody

          View all (6) GDI2 antibodies

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          Cite GDI2 Polyclonal Antibody

          • Antibody Testing Data (8)
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          GDI2 Antibody (PA5-99998) in IHC (P)

          Immunohistochemistry analysis of GDI2 in human mammary cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with GDI2 polyclonal antibody (Product # PA5-99998) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GDI2 Antibody in Western Blot (WB)
          GDI2 Antibody in Western Blot (WB)
          GDI2 Polyclonal Antibody

          Product Details

          PA5-99998

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human GDI2(Accession P50395), corresponding to amino acid residues E292-N342.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2818931

          Product Specific Information

          Antibody detects endogenous levels of total GDI2.

          Target Information

          GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: epididymis secretory sperm binding protein Li 46e; GDI beta; GDI-2; GDI-3; guanosine diphosphate (GDP) dissociation inhibitor 3; Guanosine diphosphate dissociation inhibitor 2; guanosine diphosphate dissociation inhibitor 3; Rab GDI beta; Rab GDP dissociation inhibitor beta; RAB GDP dissociation inhibitor beta-2; rab GDP-dissociation inhibitor, beta

          View more View less

          Gene Aliases: GDI-B; GDI2; Gdi3; GDIB; HEL-S-46e; RABGDIB

          View more View less

          UniProt ID: (Human) P50395, (Mouse) Q61598, (Rat) P50399

          View more View less

          Entrez Gene ID: (Human) 2665, (Mouse) 14569, (Rat) 29662

          View more View less

          Function(s)
          Rab GDP-dissociation inhibitor activity GTPase activator activity protein binding oxidoreductase activity small GTPase binding poly(A) RNA binding G-protein modulator protein-binding activity modulator
          Process(es)
          signal transduction small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of GTPase activity regulation of small GTPase mediated signal transduction oxidation-reduction process regulation of catalytic activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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