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Invitrogen
GEF5 Polyclonal Antibody
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Product Details
PA5-50117
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from internal of human ARHGEF5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total ARHGEF5 protein.
Target Information
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; ephexin3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene; unnamed protein product
Gene Aliases: 2210412D05Rik; AA717842; ARHGEF5; AW495314; GEF5; P60; TIM; TIM1
UniProt ID: (Human) Q12774, (Mouse) E9Q7D5
Entrez Gene ID: (Human) 7984, (Mouse) 54324
myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
regulation of small GTPase mediated signal transduction
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
hematopoietic stem cell homeostasis
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import
positive regulation of GTPase activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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