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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • GEFT Antibodies

          Invitrogen

          GEFT Polyclonal Antibody

          View all (5) GEFT antibodies

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          Cite GEFT Polyclonal Antibody

          • Antibody Testing Data (1)
          GEFT Antibody in Western Blot (WB)
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          GEFT Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          GEFT Antibody (PA5-106412) in WB

          Western blot analysis of GEFT in HEK-293 cell lysate (left lane: treated with blocking peptide). Samples were incubated with GEFT polyclonal antibody (Product # PA5-106412). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GEFT Antibody in Western Blot (WB)
          GEFT Polyclonal Antibody

          Product Details

          PA5-106412

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human ARHGEF25(Accession Q86VW2), corresponding to amino acid residues V323-S373.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2854085

          Product Specific Information

          Antibody detects endogenous levels of total GEFT.

          Target Information

          The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange. The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 ).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Guanine nucleotide exchange factor GEFT; p63RhoGEF; RAC/CDC42 exchange factor; Rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor (GEF) 25; Rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT

          View more View less

          Gene Aliases: 2410008H17Rik; ARHGEF25; D10Ertd610e; GEFT; p63RhoGEF

          View more View less

          UniProt ID: (Human) Q86VW2, (Mouse) Q9CWR0

          View more View less

          Entrez Gene ID: (Human) 115557, (Mouse) 52666, (Rat) 314904

          View more View less

          Function(s)
          Rho guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding guanyl-nucleotide exchange factor
          Process(es)
          regulation of Rho protein signal transduction positive regulation of GTPase activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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