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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 226 and 446 of Human GEFT|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31827 targets GEFT in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31827 immunogen is recombinant protein fragment corresponding to a region within amino acids 226 and 446 of Human GEFT.
The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GEFT; guanine nucleotide exchange factor GEFT; RAC/CDC42 exchange factor; rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor (GEF) 25; rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; rhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT
ARHGEF25; GEFT; p63RhoGEF