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This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.
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Protein Aliases: D-fructose-6-phosphate amidotransferase 1; eartha; GFAT 1; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine:fructose 6 phosphate amidotransferase 1; Glutamine:fructose-6-phosphate amidotransferase 1; harvest moon; Hexosephosphate aminotransferase 1
Gene Aliases: 2810423A18Rik; AI324119; AI449986; CMS12; CMSTA1; GFA; GFAT; GFAT 1; GFAT1; GFAT1m; GFPT; GFPT1; GFPT1L; hmn; MSLG; unm_z110
UniProt ID: (Human) Q06210, (Rat) P82808, (Mouse) P47856
Entrez Gene ID: (Human) 2673, (Rat) 297417, (Mouse) 14583, (Zebrafish) 567861
Molecular Function:
transaminase
transferase
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