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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide from C-terminus of human GFR alpha-2|
|Contains||0.02% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-33036 detects GFR alpha 2 from mouse, rat, human samples.
PA1-33036 has been successfully used in Western blot applications.
The PA1-33036 immunogen is: Synthetic peptide from C-terminus of human GFR alpha-2
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GDNF family receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GDNFRB; GFR-alpha 2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; neurturin receptor alpha; NRTNR-ALPHA; NTNR-alpha; NTNRA; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2; tyrosine kinase receptor ligand 2
GDNFRB; GFRA2; NRTNR-ALPHA; NTNRA; RETL2; TRNR2