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Proteintech
GFRA2 Polyclonal Antibody
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Product Details
21973-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GFRA2 Fusion Protein Ag16893 (270-464 aa encoded by BC041688)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Amount
58.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes all the three isoforms.
Immunogen sequence: DFHANCRAS YQTVTSCPAD NYQACLGSYA GMIGFDMTPN YVDSSPTGIV VSPWCSCRGS GNMEEECEKF LRDFTENPCL RNAIQAFGNG TDVNVSPKGP SFQATQAPRV EKTPSLPDDL SDSTSLGTSV ITTCTSVQEQ GLKANNSKEL SMCFTELTTN IIPGSNKVIK PNSGPSRARP SAALTVLSVL MLKLAL (270-464 aa encoded by BC041688)
Target Information
GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GFR-alpha 2; GFR-alpha-2; Gfra2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; TGF-beta related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; unnamed protein product
Gene Aliases: GDNFRB; GFRA2; NRTNR-ALPHA; NTNRA; RETL2; TRNR2
UniProt ID: (Human) O00451, (Mouse) O08842
Entrez Gene ID: (Human) 2675, (Mouse) 14586
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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