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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 46 and 307 of Human GGA1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29936 targets GGA1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29936 immunogen is recombinant fragment corresponding to a region within amino acids 46 and 307 of Human GGA1.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ADP-ribosylation factor binding protein 1; ARF binding protein 1; gamma adaptin ear containing; gamma ear-contain; gamma-adaptin related protein 1; gamma-adaptin-related protein 1; golgi associated; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; golgi-localized; golgi-localized, gamma ear-containing, ARF-binding protein 1