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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 20 and 280 of Human GGA2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29464 targets GGA2 in IF and WB applications and shows reactivity with Human samples.
The PA5-29464 immunogen is recombinant protein fragment corresponding to a region within amino acids 20 and 280 of Human GGA2.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ARF binding protein 2; gam; gamma adaptin ear containing; gamma-adaptin-related protein 2; golgi associated; golgi-associated, gamma adaptin ear containing, ARF binding protein 2; golgi-localized; golgi-localized, gamma ear-containing, ARF-binding protein 2; VEAR; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein
GGA2; KIAA1080; VEAR