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GGT1 Antibody (PA5-120579) in IHC (P)
Immunohistochemistry analysis of GGT1 in paraffin-embedded human breast cancer using. Samples were incubated with GGT1 Polyclonal antibody (Product # PA5-120579) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-120579
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 370-569 of human GGT1 (NP_0382652?)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914151
Product Specific Information
Positive test controls include: Jurkat, Mouse kidney. The target is usually found in the following locations: Cell membrane, Single-pass type II membrane protein.^M
^M
Immunogen sequence: KPEFYTPDDG GTAHLSVVAE DGSAVSATST INLYFGSKVR SPVSGILFNN EMDDFSSPSI TNEFGVPPSP ANFIQPGKQP LSSMCPTIMV GQDGQVRMVV GAAGGTQITT ATALAIIYNL WFGYDVKRAV EEPRLHNQLL PNVTTVERNI DQAVTAALET RHHHTQIAST FIAVVQAIVR TAGGWAAASD SRKGGEPAGY
Target Information
Glutamyltransferase (gGT) from human kidney is a membrane-bound enzyme that transfers the gamma-glutamly moiety of gamma-glutamyl compounds such as glutathione to an acceptor, which may be an amino acid or a di- or tripeptide or water. The principal functions of gGT may be hydrolysis and metabolism of glutathione. Various human gGT isoforms have been found. The molecular mass of gGT for normal kidney is 90kDa and gGT can be used as a renal cell marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD224; gamma glutamyl-transferase 1; gamma-glutamyl transpeptidase; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1; GGT 1; glutathione hydrolase 1; Glutathione hydrolase 1 proenzyme; Leukotriene-C4 hydrolase; testicular tissue protein Li 73
Gene Aliases: CD224; D22S672; D22S732; dwg; GGLUT; GGT; GGT 1; GGT-1; GGT1; Ggtp; GTG
UniProt ID: (Human) P19440, (Mouse) Q60928, (Rat) P07314
Entrez Gene ID: (Human) 2678, (Mouse) 14598, (Rat) 116568
regulation of immune system process
cellular amino acid metabolic process
glutamate metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
glutathione catabolic process
xenobiotic metabolic process
spermatogenesis
cysteine biosynthetic process
leukotriene biosynthetic process
zymogen activation
regulation of inflammatory response
proteolysis
aging
peptide modification
response to estradiol
response to lipopolysaccharide
cellular response to oxidative stress
response to tumor necrosis factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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