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Product Details
PA5-21344
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 226 of GGT1 (Uniprot ID#P19440)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.71 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_11152897
Product Specific Information
Recommended positive controls: Molt-4, Neuro2A, GL261, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (81%), Rat (80%), Pig (85%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glutamyltransferase (gGT) from human kidney is a membrane-bound enzyme that transfers the gamma-glutamly moiety of gamma-glutamyl compounds such as glutathione to an acceptor, which may be an amino acid or a di- or tripeptide or water. The principal functions of gGT may be hydrolysis and metabolism of glutathione. Various human gGT isoforms have been found. The molecular mass of gGT for normal kidney is 90kDa and gGT can be used as a renal cell marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD224; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1; GGT 1; glutathione hydrolase 1; Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain; Glutathione hydrolase 1 proenzyme; Leukotriene-C4 hydrolase; testicular tissue protein Li 73
Gene Aliases: CD224; D22S672; D22S732; dwg; GGT; GGT 1; GGT-1; GGT1; Ggtp; GTG
UniProt ID: (Human) Q9UMK1, (Mouse) Q60928
Entrez Gene ID: (Human) 2678, (Mouse) 14598
regulation of immune system process
cellular amino acid metabolic process
glutamate metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
glutathione catabolic process
xenobiotic metabolic process
spermatogenesis
cysteine biosynthetic process
leukotriene biosynthetic process
zymogen activation
regulation of inflammatory response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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