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Invitrogen
GHRHR Polyclonal Antibody
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Product Details
PA5-33583
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GHRHR.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Elephant (94%) Panda, Bat, Horse, Pig (88%) Marmoset, Zebu, Bovine, Dog (81%).
Target Information
Growth Hormone Releasing Hormone (GHRH) is a member of a family of peptide hormones that also includes VIP (vasoactive intestinal polypeptide) and PACAP (pituitary adenylate cyclase-activating polypeptide). It is a hypothalamic peptide that binds to G-protein coupled receptors to stimulate secretion and synthesis of growth hormone (GH). GHRH receptor proteins have been identified on the plasma membrane of primary human tumor cells, and are thought to be involved in the growth of a variety of cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; GHRH receptor; Ghrh-r; GHRHRpsv; GRF receptor; Growth hormone-releasing factor receptor; Growth hormone-releasing hormone receptor
Gene Aliases: GHRFR; GHRHR; GRFR; IGHD1B; IGHD4
UniProt ID: (Human) Q02643
Entrez Gene ID: (Human) 2692
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
lactation
positive regulation of cell proliferation
determination of adult lifespan
adenohypophysis development
growth hormone secretion
mammary gland development
response to insulin
cellular response to insulin stimulus
regulation of intracellular steroid hormone receptor signaling pathway
positive regulation of multicellular organism growth
hormone metabolic process
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of insulin-like growth factor receptor signaling pathway
response to estrogen
positive regulation of circadian sleep/wake cycle, non-REM sleep
hormone secretion
positive regulation of hormone secretion
cell maturation
regulation of protein metabolic process
response to glucocorticoid
establishment of localization in cell
positive regulation of growth hormone secretion
somatotropin secreting cell development
cellular response to glucose stimulus
cAMP/PKA signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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