This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-28752 targets GHS-R1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28752 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human GHS-R1.
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This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a.
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Protein Aliases: G-protein coupled receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; GHS-R; Growth hormone secretagogue receptor type 1
Gene Aliases: C530020I22Rik; GHDP; GHSR