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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 3 publications 3 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
GILZ Fusion Protein Ag3015 (43-134 aa encoded by BC018148) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.23 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: SGASVVAID NKIEQAMDLV KNHLMYAVRE EVEILKEQIR ELVEKNSQLE RENTLLKTLA SPEQLEKFQS CLSPEEPAPE SPQVPEAPGG SAV (43-134 aa encoded by BC018148)
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: delta sleep inducing peptide, immunoreactor; Delta sleep-inducing peptide immunoreactor; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; GILZ; Glucocorticoid-induced leucine zipper protein; long glucocorticoid-induced leucine zipper protein; Protein DIP; Tilz3; TSC-22 related protein; TSC-22-like protein; TSC-22-related protein; TSC-22R; TSC22 domain family 3; TSC22 domain family protein 3; TSC22 domain family, member 3; TSC22-related inducible leucine zipper 3; TSC22-related-inducible leucine zipper 3
Gene Aliases: DIP; Dsip1; DSIPI; GILZ; Tilz3; TSC-22R; TSC22D3
UniProt ID: (Human) Q99576, (Mouse) Q9Z2S7, (Rat) Q9EQZ1
Entrez Gene ID: (Human) 1831, (Mouse) 14605, (Rat) 83514
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