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Product Details
PA5-101619
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human GIMAP5(Accession Q96F15), corresponding to amino acid residues L210-Q231. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2851053 |
Target Information
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTPase IMAP family member 5; IAN-4; IAN-5; immune associated nucleotide 4 like 1; Immune-associated nucleotide-binding protein 5; immunity associated protein 3; Immunity-associated nucleotide 4 protein; Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; Immunity-associated protein 3; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5; lymphopenia
Gene Aliases: GIMAP5; HIMAP3; IAN-5; IAN4; IAN4L1; IAN5; Iddm1; IMAP3; IROD; Lyp
UniProt ID: (Human) Q96F15, (Rat) Q8K3L6
Entrez Gene ID: (Human) 55340, (Rat) 246774
Molecular Function:
small GTPase
temperature homeostasis
positive regulation of natural killer cell cytokine production
positive regulation of humoral immune response mediated by circulating immunoglobulin
positive regulation of calcium ion transport into cytosol
T cell differentiation
negative regulation of interferon-gamma production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
myeloid dendritic cell differentiation
T cell homeostasis
negative regulation of apoptotic process
negative regulation of nitric oxide biosynthetic process
positive regulation of gamma-delta T cell differentiation
positive regulation of membrane potential
positive regulation of natural killer cell mediated cytotoxicity
regulation of mitochondrial membrane permeability
negative regulation of T cell activation
negative regulation of lipid catabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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