Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-109766
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human GIMAP5 (NP_060854.2). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2.64 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2855177 |
Product Specific Information
Sequence of this protein is as follows: WGSVEEQRQQ QAELLAVIER LGREREGSFH SNDLFLDAQL LQRTGAGACQ EDYRQYQAKV EWQVEKHKQE LRENESNWAY K
Target Information
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GTPase IMAP family member 5; GTPase of the immunity-associated protein 5; IAN-4; IAN-5; immune associated nucleotide 4 like 1; Immune-associated nucleotide-binding protein 5; immunity associated protein 3; Immunity-associated nucleotide 4 protein; Immunity-associated nucleotide 4-like 1 protein; Immunity-associated nucleotide 5 protein; Immunity-associated protein 3; inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5; lymphopenia
Gene Aliases: D630024P16; E230026N22Rik; GIMAP5; HIMAP3; IAN-5; IAN4; IAN4L1; IAN5; Iddm1; IMAP3; IROD; Lyp
UniProt ID: (Human) Q96F15, (Rat) Q8K3L6, (Mouse) Q8BWF2
Entrez Gene ID: (Human) 55340, (Rat) 246774, (Mouse) 317757
Molecular Function:
small GTPase
temperature homeostasis
positive regulation of natural killer cell cytokine production
positive regulation of humoral immune response mediated by circulating immunoglobulin
positive regulation of calcium ion transport into cytosol
T cell differentiation
negative regulation of interferon-gamma production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
myeloid dendritic cell differentiation
T cell homeostasis
negative regulation of apoptotic process
negative regulation of nitric oxide biosynthetic process
positive regulation of gamma-delta T cell differentiation
positive regulation of membrane potential
positive regulation of natural killer cell mediated cytotoxicity
regulation of mitochondrial membrane permeability
negative regulation of T cell activation
negative regulation of lipid catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support