Mouse GIP shares 92.9% amino acid (aa) sequence identity with both human and rat GIP.
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
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Protein Aliases: Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic polypeptide
Gene Aliases: Gip
UniProt ID: (Mouse) P48756
Entrez Gene ID: (Mouse) 14607