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GIP Polyclonal Antibody
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FIGURE: 1 / 3
GIP Antibody (PA5-95351) in IHC (P)
Immunohistochemistry (Paraffin) analysis of GIP in paraffin-embedded section of mouse colon tissue using GIP Polyclonal Antibody (Product # PA5-95351). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution overnight at 4°C. Per... View More
Product Details
PA5-95351
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived mouse GIP recombinant protein (Position: Y44-Q85).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Mouse GIP shares 92.9% amino acid (aa) sequence identity with both human and rat GIP.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: mouse stomach tissue. IHC: mouse colon tissue, rat colon tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic peptide; Glucose-dependent insulinotropic polypeptide; Rabbit Anti GIP
Gene Aliases: Gip; Gludins; RATGLUDINS
UniProt ID: (Mouse) P48756, (Rat) Q06145
Entrez Gene ID: (Mouse) 14607, (Rat) 25040
memory
adult locomotory behavior
response to acidic pH
positive regulation of glucose transport
sensory perception of pain
endocrine pancreas development
positive regulation of insulin secretion
exploration behavior
positive regulation of cAMP-mediated signaling
positive regulation of synaptic transmission
long-term synaptic potentiation
positive regulation of glucagon secretion
triglyceride homeostasis
female pregnancy
response to carbohydrate
response to glucose
response to selenium ion
response to organic cyclic compound
response to nutrient levels
response to lipid
response to drug
response to starvation
response to amino acid
response to peptide hormone
response to axon injury
regulation of insulin secretion
digestive system development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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