Search
Invitrogen
GIPC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
GIPC1 Antibody (PA5-87978) in WB
Western blot analysis of GIPC1 in extracts of various cell lines. Samples were incubated with GIPC1 Polyclonal antibody (Product # PA5-87978) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-87978
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human GIPC1 (NP_0057071)
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Amount
60 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY; Positive Samples: A-549, HeLa, HepG2, 293T, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein
Target Information
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GAIP C-terminus-interacting protein; GLUT1 C-terminal binding protein; GLUT1 C-terminal-binding protein; GLUT1CBP; IGF-1 receptor interacting protein 1; neurophilin1-IP; PDZ domain-containing protein GIPC1; regulator of G-protein signaling 19 interacting protein 1; regulator of G-protein signalling 19 interacting protein 1; RGS-GAIP interacting protein C-terminus; RGS-GAIP interacting protein GIPC; RGS-GAIP interacting protein, C-terminus; RGS-GAIP-interacting protein; RGS19-interacting protein 1; semaF cytoplasmic domain associated protein; SemaF cytoplasmic domain-associated protein 1; SEMCAP-1; Synectin; Tax interacting protein, clone 2; Tax interaction protein 2; TIP-2; unnamed protein product
Gene Aliases: C19orf3; GIPC; GIPC1; GLUT1CBP; Glut1CIP; Hs.6454; IIP-1; NIP; OPDM2; Rgs19; RGS19IP1; SEMCAP; Semcap1; SYNECTIIN; SYNECTIN; TaxIP2; TIP-2
UniProt ID: (Human) O14908, (Rat) Q9Z254, (Mouse) Q9Z0G0
Entrez Gene ID: (Human) 10755, (Rat) 83823, (Mouse) 67903
protein targeting
G-protein coupled receptor signaling pathway
chemical synaptic transmission
glutamate secretion
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of cytokinesis
endothelial cell migration
positive regulation of melanin biosynthetic process
regulation of synaptic plasticity
cellular response to interleukin-7
presynaptic modulation of chemical synaptic transmission
positive regulation of GTPase activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support