Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
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Protein Aliases: BIR1; G protein-activated inward rectifier potassium channel 2; GIRK-2; GIRK2; Inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; KATP-2; MGC126596; Potassium channel, inwardly rectifying subfamily J member 6; potassium channel, inwardly rectifying subfamily J, member 6; potassium inwardly-rectifying channel J6; potassium inwardly-rectifying channel, subfamily J, member 6
Gene Aliases: BIR1; GIRK-2; GIRK2; hiGIRK2; KATP-2; KATP2; KCNJ6; KCNJ7; KIR3.2; KPLBS; W; weaver; wv