This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
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Protein Aliases: GCE; GCSP; Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P-protein; glycine decarboxylase, glycine cleavage system protein P); Glycine dehydrogenase (aminomethyl-transferring); glycine dehydrogenase (decarboxylating); Glycine dehydrogenase (decarboxylating), mitochondrial; glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating]; glycine dehydrogenase [decarboxylating], mitochondrial; HYGN1; mitochondrial
Gene Aliases: D030049L12Rik; D19Wsu57e; GCE; GCSP; GLDC; HYGN1