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Search Thermo Fisher Scientific
A recommended positive control is mouse small intestine tissue lysate.
At least two isoforms of GLIPR1 are known to exist; this antibody will detect both isoforms. This antibody is not expected to cross-react with other GLIPR or GLIPR-like proteins.
The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.
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Protein Aliases: GLI pathogenesis-related 1 (glioma); Glioma pathogenesis-related protein 1; GliPR 1; Protein RTVP-1; related to testes-specific, vespid, and pathogenesis proteins; related to testis-specific, vespid, and pathogenesis proteins 1; testes-specific vespid and pathogenesis protein 1
Gene Aliases: 2410114O14Rik; CRISP7; GLIPR; GLIPR1; mRTVP-1; RTVP-1; RTVP1
UniProt ID: (Human) P48060, (Mouse) Q9CWG1
Entrez Gene ID: (Human) 11010, (Mouse) 73690
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