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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1-2 µg/mL | - |
Immunocytochemistry (ICC/IF) |
0.5-2 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rat / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
7-14 |
Immunogen |
This antibody was raised against a peptide within the amino-terminal half of human GLIS1 (GLI-similar 1), which shares homology with mouse GLIS1. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.5, with 30% glycerol |
Contains |
0.035% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2793772 |
Glis1 (Gli similar 1) is also known as Gli related Kruppel-like zinc finger 1 and is encoded by the Glis1 gene located on chromosome 1 in humans. It belongs to the Kruppel-like zinc finger family of proteins that constitute mainly of transcription factors and is hence studied for its role in target gene activation and repression, specifically during embryonic development. Glis1 contains five tandem zinc finger motifs, which is the region at which it shares close homology to Glis2 and Glis 3. More recent studies on Glis1 show its interaction with Oct 3/4, Sox2 and KLF4 in efficient generation of iPSC.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Gli homologous protein 1; GLI-Kruppel family member GLI6; GLI-similar 1; GliH1; GLIS1; Glis1 Kruppel-like zinc finger protein; Zinc finger protein GLIS1; zinc finger transcription factor Gli5
Gene Aliases: Gli5; Gli6; GliH1; GLIS1
UniProt ID: (Human) Q8NBF1, (Mouse) Q8K1M4
Entrez Gene ID: (Human) 148979, (Mouse) 230587
Molecular Function:
DNA-binding transcription factor
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