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Invitrogen
GLIS2 Polyclonal Antibody
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Product Details
PA5-140108
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GLIS2. Recombinant protein control fragment (Product #RP-109026).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: VEGRFSAAPL VDLSLSPPSG LDSPNGSSSL SPERQGNGDL PPVPSASDFQ PLRYLDGVPS S
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 92%.
Target Information
Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GLI-similar 2; Kruppel-like zinc finger protein GLIS2; nephrocystin-7; Neuronal Krueppel-like protein; transcription factor; unnamed protein product; Zinc finger protein GLIS2
Gene Aliases: GLIS2; NKL; NPHP7
UniProt ID: (Human) Q9BZE0
Entrez Gene ID: (Human) 84662
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
zinc ion binding
metal ion binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
kidney development
regulation of transcription from RNA polymerase II promoter
nervous system development
central nervous system development
cell differentiation
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell differentiation involved in kidney development
hematopoietic stem cell homeostasis
positive regulation of protein localization to nucleus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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