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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 530 and 730 of Human GLIS3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30914 targets GLIS3 in WB applications and shows reactivity with Human samples.
The PA5-30914 immunogen is recombinant protein fragment corresponding to a region within amino acids 530 and 730 of Human GLIS3.
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GLI-similar 3; OK/KNS-cl.4; Zinc finger protein 515; Zinc finger protein GLIS3; ZNF515
GLIS3; NDH; ZNF515