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Invitrogen
GLP2R Polyclonal Antibody
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Product Details
PA5-111289
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human GLP2R. Recombinant protein control fragment (Product #RP-90854).
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LPGVHELPMG IPAPWGTSPL SFHRKCSLWA PGRPFLTLVL LVSIKQVTGS LLEETTRKWA QYKQACLRDL LKEPSGIFCN GTFDQYVCWP HSSPGNVSVP C
Highest antigen sequence indentity to the following orthologs: Rat - 67%, Mouse - 59%.
Target Information
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; GLP-2 receptor; GLP-2 receptor precursor; Glp2 receptor; Glucagon-like peptide 2 receptor; unnamed protein product
Gene Aliases: GLP2R
UniProt ID: (Human) O95838
Entrez Gene ID: (Human) 9340
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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