Recommended positive controls: 293T, A431, HepG2, mouse brain.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (95%), Rhesus Monkey (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycine receptor; glycine receptor alpha 2 subunit; Glycine receptor subunit alpha-2; glycine receptor, alpha 2; glycine receptor, alpha-2 polypeptide
Gene Aliases: GLR; GLRA2
Molecular Function: ligand-gated ion channel